讲师中国药科大学药学院
教师简介

孙昊鹏,男,19848月出生,博士学位,讲师。

大学开始受教育经历

·           2002.9—2006.6,中国药科大学药学理科基地班专业,获理学学士学位。

·           2006.9—2011.6,中国药科大学药物化学专业,免试推荐硕博连读,主要从事药物分子设计及化学生物学研究,获理学博士学位。

·           2011.9—至今,中国药科大学药物化学教研室,讲师。

研究工作经历

在博士及工作期间,一直从事抗肿瘤化学生物学以及药物设计学的研究,熟练掌握有机合成、光谱鉴定、生物信息学、计算机辅助药物设计等化学生物学和药物设计学的相关技术,迄今为止已发表SCI收录论文10篇,其中第一作者或者通讯作者论文7篇,2012年新发表SCI论文4篇。

4)科研成果

发表的论文

1. Hao-Peng Sun, Fei-Hong Chen, Xiao-Jian Wang, Zong-Liang Liu, Qian Yang, Xiao-Jin Zhang, Jia-Zhu, Lei Qiang, Qing-Long Guo*, Qi-Dong You*, Studies on gambogic acid (IV): Exploring structure-activity relationship with IκB kinase-beta (IKKβ). Eur. J. Med. Chem. 2012, accept, 10.1016/j.ejmech.2012.02.029 (Impact Factor=3.193)

2. Xiao-Jin zhang, Xiang-Li, Hao-Peng Sun*, Zheng-Yu Jiang, Lei Tao, Yuan Gao, Qing-Long Guo*, Qi-Dong You*. Synthesis and evaluation of novel aza-caged Garcinia xanthones. Org. Biomol. Chem., 2012accept, DOI: 10.1039/C2OB07088J. (Impact Factor=3.451)

3. Xiang Li, Xiao-Jin Zhang, Hao-Peng Sun*, Lei Zhang, Yuan Gao, Jin-Xin Wang, Qing-Long Guo, Qi-Dong You*, Synthesis and anti-timor evaluation of C37 modified derivatives of gambogic acid. Chin. J. Chem.,  2012 accept, Manuscript id: CJOC.201100693. (Impact Factor=0.773)

4. Hao-Peng Sun, Zong-Liang Liu, Xin Xue, Yuan Gao, Lei Zhang, Jin-Xin Wang, Oing-Long Guo, Qi-Dong You*Studies on chemical structure modification and structure–activity relationship of GA derivatives at C39Chemistry Biodiversity, 2012, accept. (Impact Factor=1.586)

5. Hao-Peng Sun, Jia Zhu, Fei-Hong Chen, and Qi-Dong You*, Structure-Based Pharmacophore Modeling from Multicomplex: a Comprehensive Pharmacophore Generation of Protein Kinase CK2 and Virtual Screening Based on it for Novel Inhibitors. Mol. Inf. 2011, 30, 579 - 592. (Impact Factor=3.027)

6. Hao-Peng Sun, Jia Zhu, Fei-Hong Chen, Sheng-Lie Zhang, Yuan Zhang, Qi-Dong You*, Combination of pharmacophore model development and binding mode analyses: Identification of ligand features essential for IκB kinase-beta (IKKβ) inhibitors and virtual screening based on it. Eur. J. Med. Chem. 2011, 46, 3942-3952. (Impact Factor=3.193)

7. Hao-Peng Sun, Jia Zhu, Ya-Dong Chen, Yuan Sun, Hui-Jing Zhi, Hao Li, Qi-Dong You*. Docking Study and Three-Dimensional Quantitative Structure-Activity Relationship (3D-QSAR) Analyses and Novel Molecular Design of a Series of 4-Aminoquinazolines as Inhibitors of Aurora B Kinase. Chin. J. Chem. 2011, 29, 1785-1799. (Impact Factor=0.773)

8. Liu Zong-Liang, Wang Xiao-Jian, Li Nian-Guang, Sun Hao-Peng, Wang Jin-Xin, You Qi-Dong*. Total synthesis of aldehyde-containing Garcinia natural products isomorellin and gaudichaudione A. Tetrahedron. 2011, 67, 4774-4779. (Impact Factor=3.011)

9. Dan Xu, Hao-Peng Sun, Ya-Dong Chen, Li-Ping Sun*, Qi-Dong You*. Pharmacophore Modeling and in Silico Screening Studies to Design Potential KDR Kinase Inhibitors. Chin. J. Chem. 2011, 29, 1107-1113. (Impact Factor=0.773)

10. Ya-Yu Tan, Ya-Dong Chen, Qi-Dong You*, Hao-Peng Sun, Man-Hua Li. Prediction of hERG K+ channel inhibitory potency by combining 3D-QSAR pharmacophore and 2D-QSAR models. J. Mol. Model., 2012, 18, 1023-1036. (Impact Factor: 1.871).