罗光湘,男,现任北京大学医学部病原生物学系教授,中南大学客座教授,美国肯塔基大学医学院微生物,免疫和分子遗传学系分子病毒学
承担课题:
国家自然科学基金重点项目:载脂蛋白在HCV感染和病毒颗粒组装中的作用及其分子机理
发表论文:
1. Cun
W, Jiang JY, Luo G. The C-terminal α-helix domain of apolipoprotein E is required for interaction
with hepatitis C virus (HCV) nonstructural protein
2. Sun C, Pager CT, Sarnow P, Luo G, Cate J. Hepatitis C virus
core-derived peptides inhibit genotype 1b viral genome replication via
interaction with DDX3X.PloS one, 2010, 5(9): e12826.
3. Yang
X, Haurigot V, Zhou SZ, Luo G, Couto LB. Inhibition of
hepatitis C virus replication using adeno-associated virus vector delivery of
an exogenous anti-HCV microRNA cluster. Hepatology, 2010, 52(6):1877-1887.
4. Benga WJA, Dimitrova M,
Krieger SE, Zeisel MB, Parnot M, Luo G,
Mclauchlan J, Baumert TF, Schuster C. Apolipopotein E interacts with hepatitis
C virus non-structural protein NS
5. Jiang J, Luo G. Apolipoprotein E but not B is
required for the formation of infectious hepatitis C virus particles. J Virol, 2009,
83(24): 12680-12691.
6. Ye L, Wang X, Wang S, Luo G, Wang Y, Liang H, Ho W.
Centrifugal enhancement of hepatitis C virus infection of human hepatocytes. J
Virol Methods, 2008, 148(1-2): 161-165.
7. Yang W, Hood BL, Chadwick
SL, Liu S, Watkins SC, Luo G,
Conrads TP, Wang T. Fatty acid synthase is up-regulated during hepatitis C
virus infection and regulates hepatitis C virus entry and production.
Hepatology, 2008, 48(5): 1396-1403.
8. Li Y, Ye L, Peng JS, Wang
CQ, Luo G, Zhang T, Wan Q, Ho W.
Morphine inhibits intrahepatic interferon-alpha expression and enhances
complete hepatitis C virus replication. J Infect Dis, 2007,
196(5): 719-730.
9. Keck ZY, Xia J, Cai Z, Li
TK, Owsianka AM, Patel AH, Luo G,
Foung SK. Immunogenic and functional organization of hepatitis C virus (HCV)
glycoprotein E2 on infectious HCV virions. J Virol, 2007, 81(2): 1043-1047.
10.
11.Cai Z, Cai L, Jiang J,
12.
13.Chang KS, Cai Z, Zhang C,
Sen GC, Williams BR, Luo G.
Replication of hepatitis C virus (HCV) RNA in mouse embryonic fibroblasts:
protein kinase R (PKR)-dependent and PKR-independent mechanisms for controlling
HCV RNA replication and mediating interferon activities. J Virol, 2006, 80(15):
7364-7374.
14.Zhang C, Cai Z, Kim YC,
Kumar R, Yuan F, Shi PY, Kao C, Luo G.
Stimulation of hepatitis C virus (HCV) nonstructural protein 3 (NS3) helicase
activity by the NS3 protease domain and by HCV RNA-dependent RNA polymerase.J
Virol, 2005, 79(14): 8687-8697.
15.Heller T, Saito S, Auerbach
J, Williams T, Moreen TR, Jazwinski A, Cruz B, Jeurkar N, Sapp R, Luo G, Liang TJ. An in vitro model of
hepatitis C virion production. Proc Natl Acad Sci
16.Cai Z, Zhang C, Chang KS,
Jiang J, Ahn BC, Wakita T, Liang TJ, Luo
G. Robust production of infectious hepatitis C virus (HCV) from stably HCV
cDNA-transfected human hepatoma cells. J Virol, 2005, 79(22): 13963-13973.