陈香梅，女，1971年出生。现任北京大学医学部病原生物学系讲师。2006年于哈尔滨医科大学获得医学遗传学博士学位；2006~2008年在北京大学医学部病原生物学博士后流动站做博士后研究；2008年至今在北京大学医学部病原生物学系任教。
在教学研究方面，先后承担了本科生及专科生《医学微生物学》课程的理论及实验课教学。在科研工作方面，主要从事细胞周期异常调控与肿瘤发生机制、HBV致肝癌机制等研究。目前承担的课题有国家自然科学基金青年科学基金项目“Fbx4剪接突变与肿瘤细胞周期素D1降解异常研究”；北京市科委“首都市民健康项目培育”课题“通量甲基化分析技术在肝癌分子诊断中的应用研究”；“艾滋病和病毒性肝炎等重大传染病防治”科技重大专项“十二五”课题“北京市朝阳区艾滋病和病毒性肝炎等重大传染病综合防治示范区建设研究”子课题；“艾滋病和病毒性肝炎等重大传染病防治重大专项”“十二五”课题“乙型病毒性肝炎临床治疗及优化研究”子课题。
近五年发表的主要科研论文:
1. Qing Xie, Xiangmei Chen (并列第一), Fengmin Lu, Ting Zhang, Suwen Yue, Meili Hao, Yongfeng Wang, Jingmin Zhao, Hui Zhung. Aberrant expression of miR-155 may accelerate cell proliferation by targeting SOX6 in HBV-related HCCs. Cancer. 2012;118(9):2431-42.
2. Xiangmei Chen, Tianshu Zhao, Li Li, Yongfeng Wang, Chunhui Xu, Vincent Tse, Tingzhang, Qiang Xu, Xiaoqian Liu, Fengmin Lu. CCND
3. Yongfeng Wang, Jin Cheng, Chunhui Xu, Shuang Liu , Suzhen Jiang, Qiang Xu, Xiangmei Chen*, Hui Zhuang, Fengmin Lu*. Quantitative methylation analysis reveals gender and age differences in p16INK4a hypermethylation in HBV-related HCC. Liver Int. 2012;32(3):420-8.
4. Suzhen Jiang, Ziwei Yang, Weijie Li, Xiaojun Li, Yongfeng Wang, Jiangbo Zhang, Chunhui Xu, Pei-Jer Chen, Jinlin Hou, Malcolm A. McCrae, Xiangmei Chen*, Hui Zhuang, Fengmin Lu*. Re-evaluation of the Carcinogenic Significance of Hepatitis B Virus Integration in Hepatocarcinogenesis. PLoS ONE. 2012;7(9):e40363.
5. Xiangmei Chen, Ling Zhang, Fengmin Lu, Yibin Chang, Tao Shen, Ling Wang, Hui Zhuang. Association of TNF-α genetic polymorphisms with hepatocellular carcinoma susceptibility: a case–control study in a Chinese Han population. Int J Biol Markers. 2011, 26 ( 3 ):181-187.
6. Tao Shen, Xiangmei Chen(并列第一), Weidong Zhang, Yuanlin Xi, Guanghua Cao, Yuhong Zhi, Shuiwang Wang, Chunhui Xu, Lai Wei, Fengmin Lu, Hui Zhuang. A Higher Correlation of HCV Core Antigen with CD4+ T Cell Counts Compared with HCV RNA in HCV/HIV-1 Coinfected Patients. PLoS ONE. 2011, 6(8):1-10.
7. Hao Meili, Chen, Xiangmei* , Zhang Ting, Shen Tao, Xie Qing, Xing Xiujuan, Guo Hongxi, Lu Fengmin. Impaired nuclear export of tumor-derived c-terminal truncated cyclin D1 mutant in ESCC cancer. ONCOLOGY LETTERS. 2011, 2(6), 1203-1211.
8. Tao Shen, Xiangmei Chen, Yu Chen, Qiang Xu, Fengmin Lu, Shuang Liu. Increased PD-L1 Expression and PD-L1/CD86 ratio on Dendritic Cells Were Associated with Impaired Dendritic Cells Function in HCV Infection. Journal of Medical Virology. 2010, 82(7):1152–9.
9. Shen T, Chen X, Xu Q, Lu F, Liu S. Distributional characteristics of CD25 and CD127 on CD4+ T cell subsets in chronic HCV infection. Arch Virol. 2010, 155(5):627-34.
10. Barbash O, Zamfirova P, Lin DI, Chen X, Yang K, Nakagawa H, Lu F, Rustgi AK, Diehl JA. Mutations in Fbx4 inhibit dimerization of the SCF (Fbx4) ligase and contribute to cyclin D1 overexpression in human cancer. Cancer Cell. 2008 , 14(1):68-78.
