1997毕业于首都师范大学生物系，自1999年到2002年期间，就读于河北农业大学植物病理专业从事植物病害的生物防治的研究工作。2002年就读于南开大学微生物系，攻读博士学位，2005年留校任教主要从事微生物学的教学和科研工作。
2008年1月-2009年l2月赴美国农业部和威斯康辛大学共建的森林产品实验室（USDA,Forest Product Lab）的微生物和生物技术研究所做博士后工作，从事白腐菌及褐腐菌降解木质纤维素机制的研究，该项目是美国农业部和能源部合作支持的重大项目，目的开发出新型的接触和利用纤维素的途径，为生物质能源的产生提供新的途径。在本项目中主要负责试验的设计安排，微生物分子生物学方面的研究工作，其中包括漆酶基因的克隆表达，漆酶蛋白质的分离纯化和酶学性质研究，漆酶基因在各种条件下的表达分析，农杆菌转化体系的构建和突变子的筛选鉴定等工作。近期发表的相关论文如下：
1.Dongsheng Wei, Daniel J. Yelle, John Ralph, and Kenneth E. Hammel. Multidimensional NMR analysis reveals truncated structures in wood decayed by the brown rot basidiomycete Postia placenta. Environmental Microbiology, 2011. DOI:10.1111/j.1462-2920.2010.02417.x
2.Dongsheng Wei, Carl J. Houtman, Alexander N. Kapich, Christopher G. Hunt, Daniel Cullen, and Kenneth E. Hammel. Laccase and its role in the production of extracellular reactive oxygen species during wood decay by the brown rot basidiomycete Postia placenta. Appl. Environ. Microbiol. 2010, 76（7）2091-2097
3.Dongsheng. Wei, Yinghuj. Zhang, Laijun. Xing, Mingchun Li. Agrobacterium rhizogenes-mediated transformation of a high oil-producing filamentous fungus Umbelopsis isabellina. J. Appl. Genet. 2010,51(2): 225–232.
4.Dongsheng. We, M.CH Li., X.X. Zhang, H. Zhou, L.J. Xing. A novel deta 12 fatty acid desaturase gene from methylotrophic yeast Pichia pastoris GS115. Acta. Biochimia. Polonica, 2006, 53(4): 753-759.
5.Dongsheng Wei, Mingchun Li, Xinxin Zhang, Yong Ren, Laijun Xing. Identification and characterization of a novel D12-fatty acid desaturase gene from Rhizopus arrhizus. FEBS Letters, 2004, 573: 45–50.
6.Dongsheng Wei, Mingchun Li, Xinxin Zhang, and Laijun Xing. An improvement of the site-directed mutagenesis method by combination of megaprimer, one-side PCR and DpnI treatment. Analytical Biochemistry，2004, 331: 401–403.
7.Dongsheng Wei,Hao Zhou， Zhe Yang，Xinxin Zhang， Laijun Xing， Mingchun Li. Identification of a novel delta9-fatty acid desaturase gene and its promoter from oil-producing fungus Rhizopus arrhizus. Molecular Biology Reports, 2009, 36:177–186.
8.Dongsheng Wei, Xinxin Zhang, Mingchun Li ,Yuyan Qi , Laijun Xing. Evolution-related amino acids play important role in determining regioselectivity of fatty acid desaturase from Pichia pastoris. Molecular Biology Reports, 2008, 36(3):567-573.
9.魏东盛 ,李明春, 张昕欣, 邢来君。少根根霉△12-脂肪酸脱氢酶基因在毕赤酵母中的表达.南开大学学报. 2008(1): 106-109。
10.Xinxin Zhang, Mingchun Li, Dongsheng Wei, Laijun Xing. Identification and characterization of a novel yeast ω3-fatty acid desaturase acting on long-chain n-6 fatty acid substrates from Pichia pastoris. Yeast, 2008; 25: 21–27.
11.Xuewei Zhang, Mingchun Li, Dongsheng Wei, Xiaomei Wang,Xue Chen, Laijun Xing. Disruption of the fatty acid Delta6-desaturase gene in the oil-producing fungus Mortierella isabellina by homologous recombination. Current Microbiology, 2007, 55:128–134.
12.Depei Wang, Mingchun Li, Dongsheng Wei,Yi Cai, Yinghui Zhang.Laijun Xing. Identification and Functional Characterization of the Delta 6-Fatty Acid Desaturase Gene from Thamnidium elegans. J. Eukaryot. Microbiol, 2007, 54(1): 110–117.
