谢为博，男，2010年毕业于华中农业大学，获基因组学博士学位。现任华中农业大学生命科学技术学院副教授、硕士生导师。主讲《生物信息学》和《生物信息软件综合实践》课程，教学质量评价优良。主要从事高通量基因分型技术的开发、生物信息学平台的建设及系统生物学研究。先后主持 “国家自然科学基金”、“教育部博士点基金”等项目，参与“863”、农业部948等科研项目10余项，发表科学研究论文20余篇，获得发明专利2项。

 

参与的教学研究课题：

生物信息学专业人才培养模式研究与实践，2011年湖北省高等学校省级教学研究项目

 

发表的生物信息学理论、应用相关的研究论文：

1.         Xie W, Feng Q, Yua H, Huang X, Zhao Q, Xing Y, Yu S, Han B, Zhang Q. Parent-independent genotyping for constructing an ultrahigh-density linkage map based on population sequencing.Proc Natl Acad Sci USA, 2010, 119: 151-164

2.         Wang L*, Xie W*, Chen Y, Tang W, Yang J, Ye R, Liu L, Lin Y, Xu C, Xiao J, Zhang Q. A dynamic gene expression atlas covering the entire life cycle of rice. Plant J, 2010, 61: 752-766 (* co-first author)

3.         Xie W, Chen Y, Zhou G, Wang L, Zhang C, Zhang J, Xiao J, Zhu T, Zhang Q. Single feature polymorphisms between two rice cultivars detected using a median polish method. Theor Appl Genet, 2009, 119: 151-164

4.         Cai H*, Xie W*, Zhu T, Lian X. Transcriptome response to phosphorus starvation in rice. Acta Physiol Plant, 2012, 34: 327-341 (* co-first author)

5.         Cai H, Lu Y, Xie W, Zhu T, Lian X. Transcriptome response to nitrogen starvation in rice. J Biosci, 2012, 37: 731-747

6.         Ding J, Shen J, Mao H, Xie W, Li X, Zhang Q. RNA-directed DNA methylation is involved in regulating photoperiod-sensitive male sterility in rice.Mol Plant, 2012, 5: 1210-1216

7.         Huang J, Zhao X, Weng X, Wang L, Xie W. The rice B-box zinc finger gene family: genomic identification, characterization, expression profiling and diurnal analysis. PLoS ONE, 2012, 7: e48242

8.         Tie W, Zhou F, Wang L, Xie W, Chen H, Li X, Lin Y. Reasons for lower transformation efficiency in indica rice using Agrobacterium tumefaciens-mediated transformation: lessons from transformation assays and genome-wide expression profiling. Plant Mol Biol, 2012, 78: 1-18

9.         Zhou G, Chen Y, Yao W, Zhang C, Xie W, Hua J, Xing Y, Xiao J, Zhang Q. Genetic composition of yield heterosis in an elite rice hybrid. Proc Natl Acad Sci USA, 2012, 109: 15847-15852

10.     Liu F, Chang X, Ye Y, Xie W, Wu P, Lian X. Comprehensive sequence and whole-life-cycle expression profile analysis of the phosphate transporter gene family in rice. Mol Plant, 2011, 4: 1105-1122

11.     Yu H, Xie W, Wang J, Xing Y, Xu C, Li X, Xiao J, Zhang Q. Gains in QTL Detection Using an Ultra-High Density SNP Map Based on Population Sequencing Relative to Traditional RFLP/SSR Markers. PLoS ONE, 2011, 6: e17595

12.     Zhang C, Wang J, Xie W, Zhou G, Long M, Zhang Q. Dynamic programming procedure for searching optimal models to estimate substitution rates based on the maximum-likelihood method. Proc Natl Acad Sci USA, 2011, 108: 7860-7865

13.     Wang J, Yu H, Xie W, Xing Y, Yu S, Xu C, Li X, Xiao J, Zhang Q. A global analysis of QTLs for expression variations in rice shoot at early seedling stage. Plant J, 2010, 63: 1063-1074

14.     Zhao X, Huang J, Yu H, Wang L, Xie W. Genomic survey, characterization and expression profile analysis of the peptide transporter family in rice (Oryza sativa L.). BMC Plant Biol, 2010, 10: 92

15.     Zhou Y, Cao Y, Huang Y, Xie W, Xu C, Li X, Wang S. Multiple gene loci affecting genetic background-controlled disease resistance conferred by R gene Xa3/Xa26 in rice. Theor Appl Genet, 2009, 120: 127-138

16.     Ye S, Wang L, Xie W, Wan B, Li X, Lin Y. Expression profile of calcium-dependent protein kinase (CDPKs) genes during the whole lifespan and under phytohormone treatment conditions in rice (Oryza sativa L. ssp. indica). Plant Mol Biol, 2009, 70: 311-325

17.     Qiu X, Xie W, Lian X, Zhang Q. Molecular analyses of the rice glutamate dehydrogenase gene family and their response to nitrogen and phosphorous deprivation. Plant Cell Rep, 2009, 28: 1115-1126

18.     Ouyang Y, Chen J, Xie W, Wang L, Zhang Q. Comprehensive sequence and expression profile analysis of Hsp20 gene family in rice. Plant Mol Biol, 2009, 70: 341-357

19.     Chen J, Ouyang Y, Wang L, Xie W, Zhang Q. Aspartic proteases gene family in rice: Gene structure and expression, predicted protein features and phylogenetic relation. Gene, 2009, 442: 108-118

20.     Qiu D, Xiao J, Xie W, Liu H, Li X, Xiong L, Wang S. Rice gene network inferred from expression profiling of plants overexpressing OsWRKY13, a positive regulator of disease resistance. Mol Plant, 2008, 1: 538-551

21.     Nuruzzaman M, Gupta M, Zhang C, Wang L, Xie W, Xiong L, Zhang Q, Lian X. Sequence and expression analysis of the thioredoxin protein gene family in rice. Mol Genet Genomics, 2008, 280: 139-151

22.     Nayidu N K, Wang L, Xie W, Zhang C, Fan C, Lian X, Zhang Q, Xiong L. Comprehensive sequence and expression profile analysis of PEX11 gene family in rice. Gene, 2008, 412: 59-70

23.     Gupta M, Qiu X, Wang L, Xie W, Zhang C, Xiong L, Lian X, Zhang Q. KT/HAK/KUP potassium transporters gene family and their whole-life cycle expression profile in rice (Oryza sativa). Mol Genet Genomics, 2008, 280: 437-452

24.     Fang Y, You J, Xie K, Xie W, Xiong L. Systematic sequence analysis and identification of tissue-specific or stress-responsive genes of NAC transcription factor family in rice. Mol Genet Genomics, 2008, 280: 547-563