教授华中科技大学公共卫生学院
教师简介

袁晶 博士,教授,博士生导师。长期从事环境卫生的教学与科研工作。曾负责和参与国家级研究课题多项。在研科研项目包括国家自然科学基金面上项目p73和Stestrins在MEHP致ROS介导细胞凋亡中的调控机制(No.30972437,负责人)和Sirtuins参与TCEP致细胞损伤的线粒体调控机制研究(No.81273023,负责人),973计划前期研究专项交通尾气污染与社区人群肺功能降低的联系及其机制研究(No.2011CB512102,负责人),国家973项目空气颗粒物致人群健康的基础研究第4字课题-空气颗粒物致呼吸系统早期损害的机制研究(No.2011CB503804,第一学术骨干)。参编《现代环境卫生学》(第二版)和面向21世纪教材《分子毒理学基础》(副主编)。
发表的主要学术论文:
1. Yang GT, Zhou X, Wang JS, Zhang WJ, Zheng HY, Lu WH, Yuan J*. MEHP-induced oxidative DNA damage and apoptosis in HepG2 cells correlates with p53-mediated mitochondria-dependent signaling pathway. Food Chem Toxicol. 2012; 50:2424-31
2. Jiang Y, Rao K, Yang G, Chen X, Wang Q, Liu A, Zheng H, Yuan J*. Benzo(a)pyrene induces p73 mRNA expression and necrosis in human lung adenocarcinoma H1299 cells. Environ Toxicol. 2012; 27:202-10
3. Chen X, Wang J, Qin Q, Jiang Y, Yang G, Rao K, Wang Q, Xiong W, Yuan J*. Mono-2-ethylhexyl phthalate induced loss of mitochondrial membrane potential and activation of Caspase3 in HepG2 cells. Environ Toxicol Pharmacol. 2012; 3:421-30
4. Jiang Y, Zhou X, Chen X, Yang GT, Wang Q, Rao KM, Xiong W, Yuan J*.
Benzo(a)pyrene-Induced Mitochondrial Dysfunction and Cell Death in p53-Null Hep3B Cells. Mutat Res. 2011; 726:75-83.
5. Wang Q, He MA, Gao B, Chen L, Yu ZQ, Guo H, Shi JB, Jiang P, Zhang YZ, Li LP, Sheng GY, Fu JM, Wu TC, Chen XM, Yuan J* Increased levels of lead in the blood and frequencies of lymphocytic micronucleated binucleated cells among workers from an electronic-waste recycling site. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2011; 46:669-76.
6. Yang GT, Jiang Y, Rao KM, Chen X, Wang Q, Liu AL, Xiong W, Yuan J*. Mitochondrial dysfunction and transactivation of p53-dependent apoptotic genes in BaP-treated human fetal lung fibroblasts. Hum Exp Toxicol. 2011;30:1904-13.
7. Wang Q, Wang L, Chen X, Rao KM, Lu SY, Ma ST, Jiang P, Zheng D, Xu SQ, Zheng HY, Wang JS, Yu ZQ, Zhang R, Tao Y, Yuan J*. Increased urinary 8-hydroxy-2'-deoxyguanosine levels in workers exposed to di-(2-ethylhexyl) phthalate in a waste plastic recycling site in China. Environ Sci Pollut Res Int. 2011; 18:987-96.
8. Chen L, Guo H, Yuan J*, He M, Chen D, Shi J, Yang J, Bai Y, Ju Y, Liu A, Yu Z, Li L, Sheng G, Fu J, Wu T, Chen X. Polymorphisms of GSTT1 and GSTM1 and increased micronucleus frequencies in peripheral blood lymphocytes in residents at an e-waste dismantling site in China. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2010; 45:490-7.

9. Yuan J*, Chen L, Chen D, Guo H, Bi X, Ju Y, Jiang P, Shi J, Yu Z, Yang J, Li L, Jiang Q, Sheng G, Fu J, Wu T, Chen X. Elevated serum polybrominated diphenyl ethers and thyroid-stimulating hormone associated with lymphocytic micronuclei in Chinese workers from an E-waste dismantling site. Environ Sci Technol. 2008; 42:2195-200.
10. Yang J, Liu X, Niu P, Zou Y, Gong Z, Yuan J, Wu T. Dynamic changes of XPA, XPC, XPF, XPG and ERCC1 protein expression and their correlations with levels of DNA damage in human bronchial epithelia cells exposed to benzo[a]pyrene. Toxicol Lett. 2007; 174:10-7.
11. Yuan J, Liu H, Zhou LH, Zou YL, Lu WQ. Oxidative stress and DNA damage induced by a drinking-water chlorination disinfection byproduct 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in mice. Mutat Res. 2006; 609:129-36
12. Yuan J, Wu XJ, Lu WQ, Cheng XL, Chen D, Li XY, Liu AL, Wu JJ, Xie H, Stahl T, Mersch-Sundermann V. Chlorinated river and lake water extract caused oxidative damage, DNA migration and cytotoxicity in human cells. Int J Hyg Environ Health. 2005; 208:481-8.
13. Yuan J, Yang M, Yao H, Zheng J, Yang Q, Chen S, Wei Q, Tanguay RM, Wu T. Plasma antibodies to heat shock protein 60 and heat shock protein 70 are associated with increased risk of electrocardiograph abnormalities in automobile workers exposed to noise. Cell Stress Chaperones. 2005; 10:126-35.