教育经历：
2001.6 毕业于杭州二中高中
2005.6 毕业于浙江大学药学院药学专业本科，保送直博生
2007.10-2008.10 教育部公派留学德国基尔大学人类健康研究所 博士联合培养
2010.6 博士毕业于浙江大学药理毒理与生化药学研究所
工作经历：
2010.9-2012.12 浙江大学医学神经生物学研究所 博士后
2012.12 浙江大学药理毒理与生化药学研究所 讲师
获得基金
国家自然科学基金面上项目：自噬在脑缺血/复灌过程中的神经保护作用及组胺对其调控作用机制的研究（81102429，75万）
国家自然科学青年基金：自噬在脑缺血/复灌过程中的神经保护作用及组胺对其调控作用机制的研究 2012.1-2012.12（81102429，14万，博士后一年期）
中国博士后基金：组胺调节缺血性脑损伤过程中自噬行为的机制研究 2011.1-2012.09 （2011M501022，3万）
中央高校基本科研业务费专项：自噬在脑缺血/复灌过程中的神经保护作用及组胺对其调控作用机制的研究2012.1-2012.12（8万）
发表论文：
1. Xiangnan Zhang, Haijing Yan, Yang Yuan, Jieqiong Gao, Zhe Shen, Yun Cheng, Yao Shen, Rong-Rong Wang, Xiaofen Wang, Wei-Wei Hu, Guanghui Wang, Zhong Chen*: Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondria clearance. Autophagy. (2013) Sep 1;9(9):1321-33 (IF=12.06)
2. Xiangnan Zhang, Jiaying Wu, Yuan Dou, Binbin Xia, Weibo Rong, Gerald Rimbach, Yijia Lou*: Asiatic acid protects primary neurons against C2-ceramide-induced apoptosis. Eur J Pharmcol. (2012) Mar 15;679(1-3):51-9.
3. Xiangnan Zhang, Christine Poesch-Saadatmandi, Yijia Lou, Siegfried Wolffram, Patricia Huebbe, Gerald Rimbach* : Ochratoxin A induced apoptosis in neuronal cells. Genes and Nutrition. (2009) 4(1) Mar :41-48 (IF=3.015)
4. Rongrong Wang, Xiangnan Zhang, Jianxiang Zhang, Yanying Fan, Yao Shen, Weiwei Hu, Zhong Chen*: Oxygen-Glucose Deprivation Induced Glial Scar-Like Change in Astrocytes. PLoS One. (2012) 7(5): e37574 (Co-first author, IF=4.092)
5. Yan-Ying Fan, Xiang-Nan Zhang, Ping He, Zhe Shen, Yao Shen, Xiao-Fen Wang, Wei-Wei Hu, Zhong Chen*: Transient Lack of Glucose but not O2 is Involved in Ischemic Postconditioning-induced Neuroprotection. CNS Neuroscience & Therapeutics (2012) Nov 20. doi: 10.1111/cns.12033. [Epub ahead of print] (Co-first author, IF=4.443)
6. Sonja Gaedicke, Xiangnan Zhang, Patricia Huebbe, Christine Boesch-Saadatmandi, Yijia Lou, Ingrid Wiswedel, Andreas Gardemann, Jan Frank, Gerald Rimbach: Dietary vitamin E, brain redox status and expression of Alzheimer’s disease relevant genes in rats. British Journal of Nutrition (2009), 102, 398–406
7. Sonja Gaedicke, Xiangnan Zhang, Constance Schmelzer, Yijia Lou, Frank Doering, Jan Frank, Gerald Rimbach,*: Vitamin E dependent microRNA regulation in rat liver. FEBS letters. (2008) 582: 3542-46;
8. Hongbin Zou , Hao Wu, Xiangnan Zhang, Yu Zhao, Joachim Stoekigt, Yijia Lou, Yongping Yu*: Synthesis, biological evaluation, and structure-activity relationship study of novel cytotoxic aza-caffeic acid derivatives. Bioorganic & Medicinal Chemistry. (2010) 18:6351-9
9. Zhiqiang Wang; Huanhuan Wang; Danyan Zhu; Jiaying Wu; Xiangnan Zhang; Lili Ou; Yongping Yu, Yijia Lou*：Enhanced co-expression of b-tubulin III and choline acetyltransferase in neurons from mouse embryonic stem cells promoted by icaritin in an estrogen receptor-independent manner. Chemico-Biologicol Interaction. (2009) 179: 375-385
10. Zhiqiang Wang, Xiangnan Zhang, Luoyang Qi, Huanhuan Wang, Yijia Lou*: Neuroprotective effects of icaritin against beta amyloid-induced neurotoxicity in primary cultured rat neuronal cells via estrogen-dependent pathway. Neuroscience. (2007); 145:911-922
11. Wei-xia Zhong, Yu-bin Wang, Lin Peng, Xue-zhen Ge, Jie Zhang, Shuang-shuang Liu, Xiang-nan Zhang, Zheng-hao Xu, Zhong Chen, Jian-hong Luo*:Lanthionine Synthetase C-like Protein 1 Interacts with and Inhibits Cystathionine β-Synthase: A TARGET FOR NEURONAL ANTIOXIDANT DEFENSE. J Biol Chem 2012 Oct 5;287(41):34189-201.
12. Chen-hui Zhang, Yan-ying Fan, Xiao-fen Wanga, Jia-yan Xiongd, Ying-ying Tangd, Jie-qiong Gao, Zhe Shen, Xiao-hui Song, Jing-ying Zhang, Yao Shen, Qing Li, Xiangnan Zhang, Zhong Chen*: Acidic preconditioning protects against ischemia-induced brain injury. Neurosci. Lett. 2012 Aug 8;523(1):3-8.
13. Wei-Wei Hu, Qi Fang, Zheng-Hao Xu, Hai-Jing Yan, Ping He, Kai Zhong, Yan-Ying Fan, Ying Yang, Xiang-Nan Zhang, Chun-Yang Zhang, Hiroshi Ohtsu, Tian-Le Xu, Zhong Chen*. Chronic H1-Antihistamine treatment increases seizure susceptibility after withdrawal by impairing glutamine sythetase. CNS Neuroscience & Therapeutics (2012) Aug;18(8):683-90.
